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KMID : 0377619760310020197
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Korean Jungang Medical Journal
1976 Volume.31 No. 2 p.197 ~ p.202
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Resistance of Pseudomonas Aeruginosa to Antipseudomonas Antibiotics
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Abstract
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The present studies were attempted to extend and confirm the previous studies concerning the role of appendix in immune response, and. were undertaken in order to define the distribution of lymphocyte bearing rabbit thymus specific antigen (RTA) in the rabbit lymphoid organs. For the detection of lymphocyte bearing RTA, lymphocytoxicity and indirect immunofluorescence were´ employed with goat anti-rabbit thymocyte serum.
An early hemagglutinin response in rabbit injected intravenously with 200mcg of bovine gamma globulin (BGG) was abolished by appendectomy and whole body irradiation(900g), but preserved in rabbits whose bone marrow was shielded. during irradiation and autologons appendix cells were reconstituted. These results support strongly the view that rabbit appendix apparently plays a role in immune response.
It was demonstrated by cytotoxicity test that approximatly 97% of thymocytes, 40% spleen lymphocytes, 75% of lymph node lymphocyte and 21% of appendix cells were RTA-bearing.
It was found by indirect immunofluorescene that 95% of thymocytes, 39% of spleen lymphocytes, 66% of lymph-node lymphocytes and 14% of appendix cells were RTA-bearing.
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